Check with Moment Bikes. They have a location close to the convention center and rent bikes out.

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I'm going to False Idol for some tiki drinks.

"Safe" is always a relative term, but from the Convention Center, one route is the Bayshore Bikeway

Kinda fun to ride from the convention center all the way around to the park on Coronado Island, then hop on a ferry to be dropped off right at the convention center.

The sketchiest part, though is from the convention center until you get past the Navy and shipyard complex just south of there. It's not terrible at all. Just not a true "bike path" by any stretch.

I was about to post the same about Bayshore Bikeway. There are parts of it that are great, and then there are parts where you wonder how you ended up in a junkyard. I wouldn't let that discourage you from using it, but it's good to know what you're getting into.

you can rent a bike from stay classy bikes on 25th/market. there will be a hard group ride tuesday on fiesta island 815am or paceline ride 530pm. The bayshore bikeway is best for a safe solo cruise